Episode 12
ATLS Updates | Neostigmine for Sepsis
The JournalFeed podcast for the week of March 16-21, 2026.
These are summaries from just 2 of the 5 articles we cover every week! For access to more, please visit JournalFeed.org for details about becoming a member.
The 11th edition of Advanced Trauma Life Support (ATLS) introduces major updates, including prioritization of exsanguinating hemorrhage control (xABCDE), damage control resuscitation strategies such as permissive hypotension and early transfusion, reduced crystalloid use, revised approaches to spine motion restriction, and maintaining coordinated, team-based trauma care.
This small RCT demonstrated that a low-dose continuous infusion of neostigmine in patients with septic shock resulted in downregulation of inflammatory cytokines and suggested possible improvements in organ dysfunction, illness severity, and mortality.
